Journal logos-01
– Park HA, Licznerski P, Mnatsakanyan N, Niu Y, Sacchetti S, Wu J, Polster BM, Alavian KN, Jonas EA: Inhibition of Bcl-xL prevents pro-death actions of DeltaN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity. Cell Death Differ 2017.10.1038/cdd.2017.123
– Niu Y, Moghimyfiroozabad S, Safaie S, Yang Y, Jonas EA, Alavian KN: Phylogenetic Profiling of Mitochondrial Proteins and Integration Analysis of Bacterial Transcription Units Suggest Evolution of F1Fo ATP Synthase from Multiple Modules. Journal of Molecular Evolution 2017.10.1007/s00239-017-9819-3
– Niu Y, Liu C, Moghimyfiroozabad S, Yang Y, Alavian KN: PrePhyloPro: phylogenetic profile-based prediction of whole proteome linkages. PeerJ 2017, 5:e3712.10.7717/peerj.3712
– Jonas EA, Porter GA, Beutner G, Mnatsakanyan N, Park HA, Mehta N, Chen R, Alavian KN: The mitochondrial permeability transition pore: molecular structure and function in health and disease. In Molecular Basis for Mitochondrial Signaling. Springer Series in Biological and Medical Physics, Biomedical Engineering: Springer; 2017
– Beutner G, Alavian KN, Jonas EA, Porter GA, Jr.: The Mitochondrial Permeability Transition Pore and ATP Synthase. Handb Exp Pharmacol 2017, 240:21-46.10.1007/164_2016_5

– Mnatsakanyan N, Beutner G, Porter GA, Alavian KN, Jonas EA: Physiological roles of the mitochondrial permeability transition pore. J Bioenerg Biomembr 2016.10.1007/s10863-016-9652-1
– Jonas EA, Porter GA, Beutner G, Mnatsakanyan N, Alavian KN: The Mitochondrial Permeability Transition Pore, the c-Subunit of the F1Fo ATP Synthase, Cellular Development, and Synaptic Efficiency. In The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria. John Wiley & Sons, Inc; 2016: 31-6410.1002/9781119017127.ch2
– Jonas EA, Miranda P, Gribkoff V, Alavian KN, Park H-A, Wu J, Chavez A, Zukin RS, Hardwick JM, Mnatsakanyan N: PTP and LTP: The physiological role of the permeability transition pore in learning and memory. Biochimica et Biophysica Acta (BBA)-Bioenergetics 2016, 1857:e66-e67

– Jonas EA, Porter GA, Beutner G, Mnatsakanyan N, Alavian KN: The Mitochondrial Permeability Transition Pore, the c-Subunit of the F1Fo ATP Synthase, Cellular Development, and Synaptic Efficiency. In The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria. John Wiley & Sons, Inc; 2015: 31-64
– Licznerski P, Duric V, Banasr M, Alavian KN, Ota KT, Kang HJ, Jonas EA, Ursano R, Krystal JH, Duman RS, Traumatic Stress Brain Study G: Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress. PLoS Biol 2015, 13:e1002282. 
– Jonas EA, Porter GA, Jr., Beutner G, Mnatsakanyan N, Alavian KN (2015) Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F1Fo ATP synthase. Pharmacol Res. doi:10.1016/j.phrs.2015.04.013
– Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Li H, Signore AP, Smith PJ, Gribkoff VK, Jonas EA (2015) The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole. Molecular pharmacology 87 (1):1-8. doi:10.1124/mol.114.095661
– Cotroneo E, Ashek A, Wang L, Wharton J, Dubois OD, Bozorgi SS, Busbridge M, Alavian KN, Wilkins MR, Zhao L (2015) Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat. Circ Res. doi:10.1161/CIRCRESAHA.116.305265
– Park HA, Licznerski P, Alavian KN, Shanabrough M, Jonas EA (2015) Bcl-xL is necessary for neurite outgrowth in hippocampal neurons. Antioxid Redox Signal 22 (2):93-108. doi:10.1089/ars.2013.5570
– Selvakumar T, Alavian KN, Tierney T (2015) Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus. (97):e52457. doi:doi:10.3791/52457
– Weinert M, Selvakumar T, Tierney TS, Alavian KN (2015) Isolation, culture and long-term maintenance of primary mesencephalic dopaminergic neurons from embryonic rodent brains. Journal of visualized experiments : JoVE (96). doi:10.3791/52475

– Jonas, E.A., Porter, G.A., and Alavian, K.N. (2014). Bcl-xL in neuroprotection and plasticity. Frontiers in physiology 5, 355.
– Alavian, K.N., Jeddi, S., Naghipour, S.I., Nabili, P., Licznerski, P., and Tierney, T.S. (2014). The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed. J Biomed Sci 21, 27.
– Alavian, K.N., Beutner, G., Lazrove, E., Sacchetti, S., Park, H.A., Licznerski, P., Li, H., Nabili, P., Hockensmith, K., Graham, M., et al. (2014). An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore. Proc Natl Acad Sci U S A 111, 10580-10585.

– Sacchetti, S., Alavian, K.N., Lazrove, E., and Jonas, E.A. (2013). F1FO ATPase Vesicle Preparation and Technique for Performing Patch Clamp Recordings of Submitochondrial Vesicle Membranes. JoVE.
– Li, H., Alavian, K.N., Lazrove, E., Mehta, N., Jones, A., Zhang, P., Licznerski, P., Graham, M., Uo, T., Guo, J., et al. (2013). A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis. Nature Cell Biology 15, 773-785.

– Ofengeim, D., Chen, Y.B., Miyawaki, T., Li, H., Sacchetti, S., Flannery, R.J., Alavian, K.N., Pontarelli, F., Roelofs, B.A., Hickman, J.A., et al. (2012). N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nature Neuroscience 15, 574-580.
– Gray, J.P., Alavian, K.N., Jonas, E.A., and Heart, E.A. (2012). NAD kinase (NADK) regulates the size of NADPH pool and insulin secretion in pancreatic beta cells. Am J Physiol Endocrinol Metab.
– Alavian, K.N., Dworetzky, S.I., Bonanni, L., Zhang, P., Sacchetti, S., Mariggio, M.A., Onofrj, M., Thomas, A., Li, H., Mangold, J.E., et al. (2012). Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency. Brain Res 1446, 1-11.

– Sanchez, C.E., Tierney, T.S., Gale, J.T., Alavian, K.N., Sahin, A., Lee, J.S., Mulligan, R.C., and Carter, B.S. (2011). Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation. J Neurosurg 114, 672-680.
– Gribkoff, V., Dworetzky, S., Jonas, E., and Alavian, K. (2011). Compounds and methods of modulating mitochondrial bioenergetic efficiency through an interaction with ATP synthase (complex V) and its subunits (WO Patent 2,011,150,221).
– Chen, Y.B., Aon, M.A., Hsu, Y.T., Soane, L., Teng, X., McCaffery, J.M., Cheng, W.C., Qi, B., Li, H., Alavian, K.N., et al. (2011). Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. Journal of Cell Biology 195, 263-276.
– Alavian, K.N., Li, H., Collis, L., Bonanni, L., Zeng, L., Sacchetti, S., Lazrove, E., Nabili, P., Flaherty, B., Graham, M., et al. (2011). Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nature Cell Biology 13, 1224-1233.

– Vahedi, S., Rajabian, M., Misaghian, A., Grbec, D., Simon, H.H., and Alavian, K.N. (2010). Parkinson’s disease candidate gene prioritization based on expression profile of midbrain dopaminergic neurons. J Biomed Sci 17, 66.
– Chung, C.Y., Licznerski, P., Alavian, K.N., Simeone, A., Lin, Z., Martin, E., Vance, J., and Isacson, O. (2010). The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons. Brain 133, 2022-2031.

– Simon, H.H., and Alavian, K.N. (2009). Transcriptional regulation of their survival: the Engrailed homeobox genes. Adv Exp Med Biol 651, 66-72.
– Pruszak, J., Ludwig, W., Blak, A., Alavian, K., and Isacson, O. (2009). CD15, CD24, and CD29 define a surface biomarker code for neural lineage differentiation of stem cells. Stem Cells 27, 2928-2940.
– Alavian, K.N., and Simon, H.H. (2009). Linkage of cDNA expression profiles of mesencephalic dopaminergic neurons to a genome-wide in situ hybridization database. Mol Neurodegener 4, 6.
– Alavian, K.N., Sgado, P., Alberi, L., Subramaniam, S., and Simon, H.H. (2009). Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression. Neural Dev 4, 11.

– Alavian, K.N., Scholz, C., and Simon, H.H. (2008). Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death. Mov Disord 23, 319-328.

– Sgado, P., Alberi, L., Gherbassi, D., Galasso, S.L., Ramakers, G.M., Alavian, K.N., Smidt, M.P., Dyck, R.H., and Simon, H.H. (2006). Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice. PNAS 103, 15242-15247.

– Thuret, S., Alavian, K.N., Gassmann, M., Lloyd, C.K., Smits, S.M., Smidt, M.P., Klein, R., Dyck, R.H., and Simon, H.H. (2004). The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta. J Neurochem 91, 1302-1311.
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