The causes of degeneration of midbrain dopaminergic neurons during Parkinson’s disease are not fully understood. Cellular culture ...
Mitochondrial complex V–associated large-conductance inner membrane current is regulated by cyclosporine & dexpramipexole. bit.ly/1GMDPjm
Accepted features of neurodegenerative disease include mitochondrial and protein folding dysfunction and activation of pro-death factors. Neurons that experience high metabolic demand or those foun...
Edited by Xiaodong Wang, National Institute of Biological Sciences, Beijing, China, and approved May 27, 2014 (received for review January 30, 2014)